abstract：OBJECTIVES:To describe clinical, radiological findings, and outcome in a multiethnic population of stroke survivors with basilar artery occlusive disease (BAOC). METHODS:Forty patients with infarcts in the basilar artery (BA) territory, alive 30 days after the ictus, participated in the study. BA stenosis (>50%) or oc...

journal_title：Clinical neurology and neurosurgery

authors： Ciríaco JG,Leite Cda C,dMartin Ma,Barros CV,Puglia P Jr,Caldas JG,Scaff M,Conforto AB

更新日期：2010-04-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the central nervous system caused by the JC virus; the mortality rate is high and it is usually refractory to treatment. In non-HIV patients, PML occurs as a late consequence of hematologic malignancies or during prolonged immunosupp...

journal_title：Clinical neurology and neurosurgery

authors： Yagi T,Hattori H,Ohira M,Nakamichi K,Takayama-Ito M,Saijo M,Shimizu T,Ito D,Takahashi K,Suzuki N

更新日期：2010-02-01 00:00:00

abstract：:The histopathological, immunologic, and ultrastructural findings of neurenteric cysts support an endodermal derivation. These developmental cystic lesions are generally located in the posterior mediastinum, abdomen, and pelvis and may also contain some mesodermal and neuroectodermal elements. In contrast, neurenteric ...

journal_title：Clinical neurology and neurosurgery

authors： Mittal S,Petrecca K,Sabbagh AJ,Rayes M,Melançon D,Guiot MC,Olivier A

更新日期：2010-02-01 00:00:00

abstract：:Focal task-specific dystonia affects one part of the body, occurring only during the performance of a specific task. It usually affects the hand, though it can rarely affect the orofacial region. Treatment with oral medications and botulinum toxin (BTX) usually produces only modest benefit, owing to the complexity of ...

journal_title：Clinical neurology and neurosurgery

authors： Pek CH,Seet RC,Yik JH,Lim EC

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:The study is aimed at evaluating neuroendoscopic procedures in the management of various intra-cranial intra-ventricular lesions. METHODS:We retrospectively review 24 consecutive patients harboring various intra-ventricular lesions with or without associated hydrocephalus, operated and managed by the author...

journal_title：Clinical neurology and neurosurgery

authors： Najjar MW,Azzam NI,Baghdadi TS,Turkmani AH,Skaf G

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The pathogenesis of frontal lobe atrophy (FLA) in stroke patients is unclear. We aimed to ascertain whether subcortical ischemic changes were more associated with FLA than with parietal lobe atrophy (PLA) and temporal lobe atrophy (TLA). METHODS:Brain magnetic resonance images (MRIs) from 471 Chinese ischem...

journal_title：Clinical neurology and neurosurgery

authors： Chen Y,Chen X,Xiao W,Mok VC,Wong KS,Tang WK

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Cerebral microbleeds (CMB) on gradient-echo T2*-weighted magnetic resonance image (MRI) are frequently seen in patients with cerebral diseases. In this observational study we assessed whether CMB are a predictive factor for first-ever cerebrovascular events. PATIENTS AND METHODS:This study consisted of 698 s...

journal_title：Clinical neurology and neurosurgery

authors： Nishikawa T,Ueba T,Kajiwara M,Fujisawa I,Miyamatsu N,Yamashita K

更新日期：2009-12-01 00:00:00

abstract：:A case of pseudohypoxic brain swelling, a newly defined entity, is described. The patient experienced generalized seizures and did not awake initially after a seemingly uneventful elective craniotomy for clipping of an unruptured anterior communicating artery aneurysm. Neuroimaging findings demonstrated diffuse brain ...

journal_title：Clinical neurology and neurosurgery

authors： Yokota H,Yokoyama K,Miyamoto K,Nishioka T

更新日期：2009-12-01 00:00:00

abstract：UNLABELLED:There is evidence to support that oxidative stress is increased in Parkinson's disease (PD) and contributes to degeneration of dopaminergic neurons. Uric acid (UA), a natural antioxidant in blood and brain tissue, scavenging superoxide, peroxynitrite and hydroxyl radical, was found reduced in the serum of PD...

journal_title：Clinical neurology and neurosurgery

authors： Andreadou E,Nikolaou C,Gournaras F,Rentzos M,Boufidou F,Tsoutsou A,Zournas C,Zissimopoulos V,Vassilopoulos D

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:We present a very unusual case in which a proximal posterior inferior cerebellar artery (PICA) aneurysm was located extracranially. We reviewed the PICA origin anatomy and pathology of aneurysms at this site. CLINICAL PRESENTATION:A Caucasian woman, 52 years of age, presented with a lesion at ...

journal_title：Clinical neurology and neurosurgery

authors： Dammers R,Krisht AF,Partington S

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To confirm the reported findings and clarify unknown clinical features of Churg-Strauss syndrome (CSS)-associated neuropathy and design appropriate treatment. PATIENTS AND METHODS:We assessed the clinical features of 6 patients with CSS-associated neuropathy. RESULTS:Mononeuritis multiplex was present in 4 ...

journal_title：Clinical neurology and neurosurgery

authors： Nakamura M,Yabe I,Yaguchi H,Kishimoto R,Mito Y,Fujiki N,Houzen H,Tsuji-Akimoto S,Niino M,Sasaki H

更新日期：2009-10-01 00:00:00

abstract：:We present a 67-year-old non-diabetic male who presented with muscle cramps, paresis, atrophy and fasciculations in the left leg, followed by rapidly progressive muscle stiffness and superimposed spasms which subsequently also affected the right leg and the trunk. GAD65 autoantibodies were elevated in serum and CSF, c...

journal_title：Clinical neurology and neurosurgery

authors： Holmøy T,Skorstad G,Røste LS,Scheie D,Alvik K

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Mean platelet volume (MPV) determined shortly after the onset of acute ischemic stroke represents the pre-stroke values. Data on its relationship to stroke severity/outcome have been conflicting. We related MPV to infarct volume on CT brain scans and risk of death/dependence 7 days and 3 months post-stroke. ...

journal_title：Clinical neurology and neurosurgery

authors： Pikija S,Cvetko D,Hajduk M,Trkulja V

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of Parkinson's disease (PD) on unpaid, non-professional caregiver (CG) social relationships and related issues, as well as home-help services, over the time-course of the disease. MATERIALS AND METHODS:Cross-sectional telephone survey using a structured questionnaire where CGs were div...

journal_title：Clinical neurology and neurosurgery

authors： Lökk J

更新日期：2009-09-01 00:00:00

abstract：:The authors describe clinical and radiological features of a 32-year-old male patient with a posterior fossa lesion. The radiological characteristics resembled an extra-axial lesion; a meningioma, with attachment to the tentorium and petrous bone. The histological diagnosis was classical medulloblastoma. We review lit...

journal_title：Clinical neurology and neurosurgery

authors： Furtado SV,Venkatesh PK,Dadlani R,Reddy K,Hegde AS

更新日期：2009-07-01 00:00:00

abstract：AIMS:Muscle biopsy is an important diagnostic modality and screening test for the diagnosis of dystrophinopathies. Sometimes muscle biopsies are needed for the diagnosis when genetic tests are inconclusive and are also useful for immunoblotting assay of the dystrophin protein. However, the procedure is painful, require...

journal_title：Clinical neurology and neurosurgery

authors： Tanveer N,Sharma MC,Sarkar C,Gulati S,Kalra V,Singh S,Bhatia R

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:During recent years, sialorrhea in Parkinson's disease (PD) has been treated with botulinum toxin type A (BT-A); however, there are no data describing its effects on swallowing dynamics in this group of patients. OBJECTIVE:To investigate whether injection of BT-A into the parotid glands interferes with the ...

journal_title：Clinical neurology and neurosurgery

authors： Nóbrega AC,Rodrigues B,Melo A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate aortic atheromas in stroke subgroups. METHODS:Two hundred consecutive subjects had acute ischemic stroke confirmed by diffusion-weighted imaging (DWI) (195 cases) or computerized tomography (5 cases). Multidetector computed tomographic angiography (MDCTA) (16- or 64-...

journal_title：Clinical neurology and neurosurgery

authors： Kaya D,Yildiz E

更新日期：2009-06-01 00:00:00

abstract：:Essential Tremor (ET) is characterized by a 4-12-Hz postural and kinetic tremor, most commonly affecting the upper limbs. Deep brain stimulation (DBS) of the thalamus (Vim) has been found to be highly effective in severe/refractory forms of ET. Intra-operative assessment of tremor is performed using clinical methods b...

journal_title：Clinical neurology and neurosurgery

authors： Papapetropoulos S,Gallo BV,Guevara A,Singer C,Mitsi G,Lyssikatos C,Jagid JR

更新日期：2009-05-01 00:00:00

abstract：:This study aims to achieve the complete removal of trigeminal schwannoma (TS) while preserving cranial nerve function. We focused on the outcomes of different surgical approaches and address the contributions of different operative techniques. Forty-two TS cases, treated surgically in Qilu Hospital during a 12-year pe...

journal_title：Clinical neurology and neurosurgery

authors： Zhang L,Yang Y,Xu S,Wang J,Liu Y,Zhu S

更新日期：2009-04-01 00:00:00

abstract：:Spinal meningiomas are uncommon entities that fortunately burden only a small minority of patients. Notwithstanding their overwhelmingly benign propensity, the occurrence of extramedullary meningioma may nonetheless cause significant morbidity and possible mortality. The consideration therefore, of spinal meningioma i...

journal_title：Clinical neurology and neurosurgery

authors： Saraceni C,Harrop JS

更新日期：2009-04-01 00:00:00

abstract：:Tic disorders are commonly considered to be childhood syndromes. Newly presenting tic disorders during adulthood are uncommon and mostly described in relation to an acquired brain lesion or as incidental tics, particularly in context with other neurological or psychiatric diseases. Tic disorder involving the ears is e...

journal_title：Clinical neurology and neurosurgery

authors： Agrawal A,Shrestha R

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:Spinal intramedullary tuberculosis is a rare disease. This study aims to acquaint readers with its clinicoradiological features and emphasizes the importance of early treatment in intramedullary spinal tuberculosis. MATERIALS AND METHODS:Retrospective analysis was conducted from 1985 to 2006 over a period o...

journal_title：Clinical neurology and neurosurgery

authors： Ramdurg SR,Gupta DK,Suri A,Sharma BS,Mahapatra AK

更新日期：2009-02-01 00:00:00

abstract：:Paintball is an "extreme sport" that has been steadily growing in popularity since the early 1980s. Although this activity is considered recreational, there are a number of inherent dangers associated. Most notably, the number of head and neck injuries due to paintball participation has been increasing in recent years...

journal_title：Clinical neurology and neurosurgery

authors： John N,Leach JL,Rachana T,Mangano FT

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To review the direct and indirect effects on the central nervous system (CNS) of systemically administered immuno-modulatory therapies in use or under evaluation for the relapsing forms of multiple sclerosis (MS). METHODS:We summarize data published by our own lab and by others that delineate the effects of ...

journal_title：Clinical neurology and neurosurgery

authors： Antel JP,Miron VE

更新日期：2008-11-01 00:00:00

abstract：:No specific treatment exists for patients with multiple sclerosis (MS) who fail to respond to conventional immunosuppressive and immunomodulating modalities. Furthermore, no method is available for regeneration of existing defect in the central nervous system (CNS). The ultimate goals of MS treatment, similarly to oth...

journal_title：Clinical neurology and neurosurgery

authors： Slavin S,Kurkalli BG,Karussis D

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Chronic subdural haematoma is a disease of the elderly and surgery in these patients carries a much higher risk. The common surgical procedures for chronic subdural haematoma include twist drill craniostomy, burr hole evacuation or craniotomy. The aim of this study was to analyse the results of twist drill cr...

journal_title：Clinical neurology and neurosurgery

authors： Ramnarayan R,Arulmurugan B,Wilson PM,Nayar R

更新日期：2008-09-01 00:00:00

abstract：:A 26-year-old female presented with severe lumbodorsal pain and hypesthesia in the right lower extremity. MRI of the spine revealed multiple lesions from L1 to S5; the largest was located at the conus medullaris. Diagnostic exploration revealed caseous, ivory-colored granulation tissue adhered to the conus medullaris ...

journal_title：Clinical neurology and neurosurgery

authors： Bao XY,Ding XH,Lu YC

更新日期：2008-09-01 00:00:00

abstract：:Intraventricular cavernomas are extremely infrequent and only 11 cases of cavernous hemangioma to occur at the foramen of Monro have been reported in the literature. This 56 years old patient was admitted with progressive and intractable headache of 10 days of evolution. He was known to suffer familial multiple cavern...

journal_title：Clinical neurology and neurosurgery

authors： Prat R,Galeano I

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:The natural history of giant intracranial aneurysms is generally morbid. Mortality and morbidity associated with giant aneurysms is also higher than for smaller aneurysms. This study was carried out to assess the demographic profile, presenting features, complications, and outcome after surgical treatment of...

journal_title：Clinical neurology and neurosurgery

authors： Sharma BS,Gupta A,Ahmad FU,Suri A,Mehta VS

更新日期：2008-07-01 00:00:00

abstract：:A variety of immunological abnormalities have been reported in some patients with amyotrophic lateral sclerosis (ALS). It has been postulated that a disturbance of immunoregulation may play a role in the degeneration of motor neurons in ALS. We describe a 62-year-old man with a 9-month history of slowly progressive mu...

journal_title：Clinical neurology and neurosurgery

authors： Yamazaki T,Suzuki M,Irie T,Watanabe T,Mikami H,Ono S

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:Understanding the microanatomy of the proximal middle cerebral artery (M1) and its early branches is very important for aneurysm surgery in this region. However, few articles provide detailed descriptions of such aneurysms. We report the angiographic characteristics of a series of M1 aneurysms and our experie...

journal_title：Clinical neurology and neurosurgery

authors： Park DH,Kang SH,Lee JB,Lim DJ,Kwon TH,Chung YG,Lee HK

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:Most imaging studies of mild cognitive impairment (MCI) have focused on gray matter alterations, although many MCI patients demonstrate subcortical vascular changes. We investigated the changes of the hippocampal area and various white matter areas in MCI patients with using diffusion tensor imaging (DTI), a...

journal_title：Clinical neurology and neurosurgery

authors： Shim YS,Yoon B,Shon YM,Ahn KJ,Yang DW

更新日期：2008-06-01 00:00:00

abstract：:Patients, in particular recipients of orthotopic liver transplants, receiving the immunosuppressant tacrolimus (FK-506), are at risk for developing central neurotoxic adverse events. We report the occurrence of a tacrolimus-induced peripheral neurotoxic event, i.e. pure motor axonal polyneuropathy of the lower limbs i...

journal_title：Clinical neurology and neurosurgery

authors： De Weerdt A,Claeys KG,De Jonghe P,Ysebaert D,Chapelle T,Roeyen G,Jorens PG

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:Central neurocytoma is a rare intraventricular brain tumor that affects young adults and presents with increased intracranial pressure secondary to obstructive hydrocephalus. Typically, it has a favorable prognosis after adequate surgical intervention, but in some cases the clinical course is more aggressive. I...

journal_title：Clinical neurology and neurosurgery

authors： Chen CL,Shen CC,Wang J,Lu CH,Lee HT

更新日期：2008-02-01 00:00:00

abstract：:Tardive dyskinesia (TD) is a hyperkinetic movement disorder induced by dopamine receptor blocking drugs (DRBDs). TD typically presents with stereotypy or dystonia, but may also cause akathisia, myoclonus, or tremor. However, no detailed reports of gait abnormalities have been documented. We report three patients expos...

journal_title：Clinical neurology and neurosurgery

authors： Kuo SH,Jankovic J

更新日期：2008-02-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a demyelinating neurologic disorder caused by a polyomavirus, called JC virus. PML affects mainly immunocompromised hosts. We report a case of PML as first manifestation of sarcoidosis in a previously healthy man. Treatment with cidofovir, resulted in a neurological ...

journal_title：Clinical neurology and neurosurgery

authors： De Raedt S,Lacor P,Michotte A,Flamez A,Ebinger G

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to retrospectively review the surgical outcome of 309 craniopharyngioma cases treated by a single neurosurgeon in China. PATIENTS AND METHODS:A total of 309 cases of craniopharyngioma that were treated surgically from January 1996 to May 2006. Among them, 162 (52.4%) pa...

journal_title：Clinical neurology and neurosurgery

authors： Shi XE,Wu B,Fan T,Zhou ZQ,Zhang YL

更新日期：2008-02-01 00:00:00

abstract：:Ependymomas account for 3-9% of all neuroepithelial tumors. A peculiar variant of ependymoma known as "giant cell ependymoma" ("GCE") is especially rarely reported, it may pose some difficulties for the diagnosing neuropathologist. Here we present a case of a giant cell ependymoma occuring in a 17-year-old patient wit...

journal_title：Clinical neurology and neurosurgery

authors： Adamek D,Dec M,Sobol G,Urbanowicz B,Jaworski M

更新日期：2008-02-01 00:00:00

abstract：:Non-pituitary lesions account for a minority of sellar region abnormalities. We report the unusual occurrence of non-pituitary sellar/suprasellar lesions in a mother and her two daughters. Each of these cases was diagnosed and managed differently, illustrating the relative importance of radiographic imaging, tumor mar...

journal_title：Clinical neurology and neurosurgery

authors： Gabeau-Lacet D,Grant E,Stemmer-Rachamimov A,Yock T,Tarbell NJ

更新日期：2008-02-01 00:00:00